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Rabbit
Anti-LITAF/PE-Cy5
Cat. Number:
bs-18300R-PE-Cy5
Quantity size:
100ul
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppresor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2008]
Also known as:
Lipopolysaccharide induced TNF alpha factor;
CMT1C;
FLJ38636;
Lipopolysaccharide induced TNF alpha factor;
Lipopolysaccharide induced TNF factor;
Lipopolysaccharide induced tumor necrosis factor alpha factor;
Lipopolysaccharide-induced tumor necrosis factor-alpha factor;
LITAF;
LITAF_HUMAN;
LPS induced TNF alpha factor;
LPS-induced TNF-alpha factor;
MGC116698;
MGC116700;
MGC116701;
MGC125274;
MGC125275;
MGC125276;
p53 induced gene 7 protein;
p53-induced gene 7 protein;
PIG 7;
PIG7;
SIMPLE;
Small integral membrane protein of lysosome/late endosome;
TP53I7;
Tumor protein p53 inducible protein 7.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with:
(predicted: )
●
Immunogen: KLH conjugated synthetic peptide derived from human LITAF.
●
Predicted Molecular Weight: 17kDa.
Storage:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Application:
Excitation spectrum: 488nm,561nm,649nm
Emission spectrum: 667nm
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.