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Cat. Number:

bs-18866R-RBITC

Quantity size:

100ul

Concentration:

1mg/ml  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

RSC1A1 is 617 amino acid nuclear protein that localizes to the inner side of the plasma membrane and the Golgi apparatus. Expressed in small intestine, kidney and brain, RSC1A1 mediates transcriptional and post-transcriptional regulation of Na(+)-D-glucose cotransporter SGLT-1 (sodium/glucose cotransporter 1). RSC1A1 is thought to inhibit the dynamin-dependent release of SGLT-1-containing vesicles from the TGN (trans-Golgi network). Mutations in the gene encoding RSC1A1 may lead to leptin-independent up-regulation of food intake, which is suggested to be partially responsible for obesity. The gene encoding is RSC1A1 located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.

Also known as:

Regulator Of Solute Carriers 1; Regulatory Solute Carrier Protein, Family 1, Member 1; Transporter Regulator RS1; Regulatory Solute Carrier Protein Family 1 Member 1; HRS1; RS1; RSCA1_HUMAN;

Specificity:

Storage:

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Application:

Excitation spectrum: 540nm
Emission spectrum: 625nm
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.