www.bioss.com.cn
400-901-9800
sales@bioss.com.cn
techsupport@bioss.com.cn

Cat. Number:

bs-9389R-PE-Cy7

Quantity size:

100ul

Concentration:

1mg/ml  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

MuRF1 (RNF28), MuRF2 (RNF29) and MuRF3 (RNF30) are a specific class of RING finger proteins expressed in striated muscle tissues that act as signaling molecules and cytoskeletal adaptors. The MuRF proteins contain a conserved N-terminal RING domain and zinc-binding B-box motif in addition to two coiled-coil motifs in their central regions. In muscle cells, MuRF2 regulates gene expression and protein turnover. It localizes to the cytoplasm, but under atrophic conditions it is detected in the nucleus. MuRF2 can form oligomers with various other proteins, including titin and myosin, during sarcomere assembly. Endogenous MuRF2 associates with the sarcomeric M-band in cardiomyocytes. There are at least four isoforms of MuRF2.

Also known as:

MURF 2; MURF-2; MuRF2; Muscle specific ring finger 2; Muscle specific RING finger protein 2; Muscle-specific RING finger protein 2; ring finger protein 29; RNF 29; RNF29; TRI55_HUMAN; TRIM 55; Trim55; Tripartite motif containing 55; Tripartite motif containing protein 55; Tripartite motif-containing protein 55.

Specificity:

Storage:

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Application:

Excitation spectrum: 488nm,561nm,743nm
Emission spectrum: 785nm
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.