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Rabbit
Anti-MBNL1/Gold
Cat. Number:
bs-19111R-Gold
Quantity size:
100ul
35nm
Concentration:
0.4mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
MBNL1 is a deduced 370 amino acid protein which is predominantly expressed in skeletal muscle, prostate, lung, heart, small intestine, ovary and placenta tissues. MBNL1 and MBNL2, which associate with ex-panded CUG repeats in vitro, both localize to the nuclear foci in both DM1 and DM2 (myotonic dystrophy types 1 and 2), suggesting that the nuclear accumulation of mutant RNA is pathogenic in DM1, therefore implicating MBNL1 and 2 in the pathogenesis of both disorders.
Also known as:
Muscleblind-like 1;
EXP;
EXP35;
EXP40;
EXP42;
KIAA0428;
MBNL;
MBNL protein;
MBNL1;
MBNL1_HUMAN;
Muscleblind 41kD isoform;
Muscleblind like;
Muscleblind like protein 1;
Muscleblind like splicing regulator 1;
Muscleblind-like protein 1;
Triplet expansion RNA binding protein;
Triplet-expansion RNA-binding protein.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with:
(predicted: )
●
Immunogen: KLH conjugated synthetic peptide derived from human MBNL1.
●
Predicted Molecular Weight: 41kDa.
Storage:
0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
Application:
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.