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Rabbit
Anti-RBBP7/RbAp46/PE-Cy5.5
Cat. Number:
bs-19740R-PE-Cy5.5
Quantity size:
100ul
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
Also known as:
G1/S transition control protein binding protein RbAp46;
Histone acetyltransferase type B subunit 2;
Histone binding protein RBBP 7;
Histone binding protein RBBP7;
Histone-binding protein RBBP7;
MGC138867;
MGC138868;
Nucleosome remodeling factor subunit RBAP46;
Nucleosome-remodeling factor subunit RBAP46;
RbAp 46;
RBAP46;
RBBP 7;
RBBP-7;
RBBP7;
RBBP7_HUMAN;
Retinoblastoma binding protein 7;
Retinoblastoma binding protein p46;
Retinoblastoma binding protein RbAp46;
Retinoblastoma protein associated protein 46;
Retinoblastoma-binding protein 7;
Retinoblastoma-binding protein p46;
Retinoblastoma-binding protein RbAp46.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with:
(predicted: )
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Immunogen: KLH conjugated synthetic peptide derived from human RBBP7/RbAp46.
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Predicted Molecular Weight: 48kDa.
Storage:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Application:
Excitation spectrum: 496,564nm,675nm
Emission spectrum: 578nm,695nm
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.