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Rabbit
Anti-RASGRP2/AP
Cat. Number:
bs-19735R-AP
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Three alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Also known as:
Calcium and DAG-regulated;
Calcium and DAG-regulated guanine nucleotide exchange factor I;
Calcium-and diacylglycerol-regulated guanine nucleotide exchange factor I;
CalDAG-GEFI;
Cdc25 like protein;
Cdc25-like protein;
F25B3.3 kinase like protein;
F25B3.3 kinase-like protein;
GRP2_HUMAN;
hCDC25L;
RAS guanyl releasing protein 2;
RAS guanyl-releasing protein 2;
Rasgrp2.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with:
(predicted: )
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Immunogen: KLH conjugated synthetic peptide derived from human RASGRP2.
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Predicted Molecular Weight: 69kDa.
Storage:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Application:
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.