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Rabbit
Anti-PDE8B/PE-Cy5.5
Cat. Number:
bs-12588R-PE-Cy5.5
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2010]
Also known as:
3' 5' cyclic nucleotide phosphodiesterase 8B;
3'5' cyclic nucleotide phosphodiesterase 8B;
Cell proliferation-inducing gene 22 protein;
FLJ11212;
High affinity cAMP specific and IBMX insensitive 3' 5' cyclic phosphodiesterase 8B;
High affinity cAMP specific and IBMX insensitive 3'5' cyclic phosphodiesterase 8B;
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B;
High-affinity cAMP-specific and IBMX-insensitive 3'5'-cyclic phosphodiesterase 8B;
HSPDE 8B;
HsPDE8B;
PDE 8B;
PDE8B;
PDE8B_HUMAN;
Phosphodiesterase 8B;
Phosphodiesterase8B;
PIG22.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with:
(predicted: )
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Immunogen: KLH conjugated synthetic peptide derived from human PDE8B.
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Predicted Molecular Weight: 99kDa.
Storage:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Application:
Excitation spectrum: 496,564nm,675nm
Emission spectrum: 578nm,695nm
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.