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Rabbit
Anti-PDE4C/BF488
Cat. Number:
bs-9962R-BF488
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
Also known as:
DPDE 1;
DPDE1;
MGC126222;
PDE 21;
PDE 4C;
PDE21;
Pde4c;
PDE4C_HUMAN;
Phosphodiesterase 4C;
Phosphodiesterase 4C cAMP specific;
Phosphodiesterase 4C, cAMP specific (phosphodiesterase E1 dunce homolog, Drosophila);
Phosphodiesterase E1 dunce homolog;
Phosphodiesterase E1 dunce homolog Drosophila;
Phosphodiesterase type 4C.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with:
(predicted: )
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Immunogen: KLH conjugated synthetic peptide derived from human PDE4C.
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Predicted Molecular Weight: 80kDa.
Storage:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Application:
Excitation spectrum: 495nm
Emission spectrum: 519nm
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.