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Rabbit
Anti-PLOD2/Gold
Cat. Number:
bs-12731R-Gold
Quantity size:
100ul
10nm
Concentration:
0.4mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Also known as:
2-oxoglutarate 5-dioxygenase 2;
LH2;
Lysine hydroxylase 2;
Lysyl hydroxylase 2;
OTTHUMP00000215204;
OTTHUMP00000215205;
OTTHUMP00000215206;
PLOD 2;
Plod2;
PLOD2_HUMAN;
Procollagen lysine 2 oxoglutarate 5 dioxygenase 2;
Procollagen lysine, 2 oxoglutarate 5 dioxygenase (lysine hydroxylase) 2;
Procollagen-lysine;
Telopeptide lysyl hydroxylase;
TLH.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with:
(predicted: )
●
Immunogen: KLH conjugated synthetic peptide derived from human PLOD2.
●
Predicted Molecular Weight: 85kDa.
Storage:
0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
Application:
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.