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Mouse
Anti-BCL-6/APC
Cat. Number:
bsm-51096M-APC
Quantity size:
100ul
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015]
Also known as:
B-Cell CLL/Lymphoma 6;
Zinc Finger Protein 51;
Zinc Finger And BTB Domain-Containing Protein 27;
B-Cell Lymphoma 5 Protein;
Protein LAZ-3;
ZBTB27;
ZNF51;
BCL-5;
BCL-6;
BCL5;
LAZ3;
Lymphoma-Associated Zinc Finger Gene On Chromosome 3;
Cys-His2 Zinc Finger Transcription Factor;
Zinc Finger Transcription Factor BCL6S;
B-Cell Lymphoma 6 Protein Transcript;
B-Cell Lymphoma 6 Protein;
BCL6A;
BCL6_HUMAN;
Specificity:
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Mouse Monoclonal(Clone number:6F5) IgG1, affinity purified by Protein G.
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Reacts with:
(predicted: )
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Immunogen: KLH conjugated synthetic peptide derived from human BCL-6.
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Predicted Molecular Weight: 78kDa.
Storage:
Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.05M PB, pH 7.5. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Application:
Excitation spectrum: 650nm
Emission spectrum: 660nm
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.