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Rabbit  Anti-ARTS/SEPT4/Cy5.5
Cat. Number:
bs-7096R-Cy5.5
Quantity size:
100ul
Concentration:
1mg/ml  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
This gene is a member of the septin family of nucleotidebinding proteins, originally described in yeast as cell divisioncycle regulatory proteins. Septins are highly conserved in yeast,Drosophila, and mouse, and appear to regulate cytoskeletalorganization. Disruption of septin function disturbs cytokinesisand results in large multinucleate or polyploid cells. This gene ishighly expressed in brain and heart. Alternatively splicedtranscript variants encoding different isoforms have been describedfor this gene. One of the isoforms (known as ARTS) is distinct; itis localized to the mitochondria, and has a role in apoptosis andcancer. [provided by RefSeq, Nov 2010].
Also known as:
Apoptosis Related Protein TGFb Signalling; Apoptosis-related protein in the TGF-beta signaling pathway; ARTS; bradeion; Bradeion beta; Brain protein H5; CE5B3; CE5B3 beta; cell division control-related protein 2; cerebral protein 7; H5 antibody hCDCREL-2; hucep-7; peanut-like 2; Peanut-like protein 2; PNUTL2; SEPT4; SEPT4_HUMAN; septin 4; Septin-4.
Specificity:
Rabbit Polyclonal IgG, affinity purified by Protein A.
Reacts with: (predicted: )
Immunogen: KLH conjugated synthetic peptide derived from human ARTS (91-150aa).
Predicted Molecular Weight: 55kDa.
Storage:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Application:

Excitation spectrum: 675nm
Emission spectrum: 694nm
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.