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Recombinant human TBK1 protein, N-His
Catalog Number:
bs-42100P
General Information
QC Testing
Purity:
>90% as determined by SDS-PAGE
Usage Guide
Storage:
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
Background:
The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. [provided by RefSeq, Oct 2010]
Figures
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.