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Recombinant human RANK protein, C-His (HEK293)
Catalog Number:
bs-43608P
General Information
Species:
Human
Host:
HEK293 cell
Predicted MW:
21.2
Tags:
C-His
QC Testing
Endotoxin:
Not analyzed
Purity:
>90% as determined by SDS-PAGE
Purification:
AC
Concentration:
>0.5mg/ml
Usage Guide
Storage:
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
Background:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Aug 2012]
Figures
VALIDATION IMAGES
 
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.