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Recombinant human ROR1 protein, C-His (HEK293)
Catalog Number:
bs-43624P
General Information
Species:
Human
Host:
HEK293 cell
AA Seq:
30-403/937
Predicted MW:
43.1
Tags:
C-His
QC Testing
Endotoxin:
Not analyzed
Purity:
>90% as determined by SDS-PAGE
Concentration:
>1mg/ml
Usage Guide
Storage:
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
Background:
This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2012]
Figures
VALIDATION IMAGES
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.