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Recombinant human FOLR2 protein, N-His
Catalog Number:
bs-42188P
General Information
Species:
Human
Host:
E.coli
AA Seq:
22-228/255
Predicted MW:
26.4
Tags:
N-His
QC Testing
Endotoxin:
Not analyzed
Purity:
>90% as determined by SDS-PAGE
Purification:
AC
Concentration:
>1mg/ml
Usage Guide
Storage:
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
Background:
The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Figures
VALIDATION IMAGES
 
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.