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Rabbit
Anti-Dexras1/PE-Cy7
Cat. Number:
bs-14284R-PE-Cy7
Quantity size:
100ul
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
This gene encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. The encoded protein is an activator of G-protein signaling and acts as a direct nucleotide exchange factor for Gi-Go proteins. This protein interacts with the neuronal nitric oxide adaptor protein CAPON, and a nuclear adaptor protein FE65, which interacts with the Alzheimer's disease amyloid precursor protein. This gene may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. Epigenetic inactivation of this gene is closely correlated with resistance to dexamethasone in multiple myeloma cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2011]
Also known as:
Activator of G protein signaling 1;
Activator of G protein signaling;
Activator of G-protein signaling 1;
AGS 1;
AGS1;
Dexamethasone induced ras related protein 1;
Dexamethasone-induced ras protein 1;
Dexamethasone-induced Ras-related protein 1;
Dexras 1;
MGC:26290;
RAS dexamethasone induced 1;
Ras protein, Dexamethasone-induced, 1;
Ras related protein;
RASD 1;
Rasd1;
RASD1_HUMAN.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with:
(predicted: )
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Immunogen: KLH conjugated synthetic peptide derived from human Dexras1.
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Predicted Molecular Weight: 31kDa.
Storage:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Application:
Excitation spectrum: 488nm,561nm,743nm
Emission spectrum: 785nm
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.