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Rabbit
Anti-phospho-DLC1 (Ser567)/AF350
Cat. Number:
bs-14339R-AF350
Quantity size:
100ul
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
This gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.[provided by RefSeq, Apr 2010]
Also known as:
p-DLC1 (Ser567);
DLC1 (phospho S567);
p-DLC1 (phospho S567);
ARHGAP 7;
ARHGAP7;
Deleted in liver cancer 1;
Deleted in liver cancer 1 protein;
DLC 1;
Dlc-1;
DLC1;
FLJ21120;
HP;
HP protein;
KIAA1723;
p122 RhoGAP;
RHG07_HUMAN;
Rho GTPase activating protein 7;
Rho GTPase-activating protein 7;
Rho type GTPase activating protein 7;
Rho-type GTPase-activating protein 7;
StAR related lipid transfer protein 12;
StAR-related lipid transfer protein 12;
STARD 12;
StARD12;
START domain containing protein 12;
START domain-containing protein 12.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with:
(predicted: )
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Immunogen: KLH conjugated Synthesised phosphopeptide derived from human DLC1 around the phosphorylation site of Ser567.
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Predicted Molecular Weight: 171kDa.
Storage:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Application:
Excitation spectrum: 346nm
Emission spectrum: 422nm
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.