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Cat. Number:

bs-14568R-FITC

Quantity size:

100ul

Concentration:

1mg/ml  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

ELMOD2 is a 293 amino acid protein that is one of six human proteins that contain an ELMO domain. ELMOD2 is thought to interact with DOCK1 through a SH3-binding site, which enhances the guanine nucleotide exchange factor (GEF) activity of DOCK1. Therefore, ELMOD2 may also be part of a complex with DOCK1 and Rac1 that is required to activate Rac Rho small GTPases. Evidence of decreased ELMOD2 expression in lung of individuals with familial idiopathic pulmonary fibrosis (IPF) suggests that defects in the gene encoding ELMOD2 may be linked to susceptibility for familial IPF.

Also known as:

9830169G11Rik; ELMD2_HUMAN; ELMO domain containing 2; ELMO domain containing protein 2; ELMO domain-containing protein 2; ELMO/CED 12 domain containing 2; ELMOD2; MGC10084.

Specificity:

Storage:

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Application:

Excitation spectrum: 495nm
Emission spectrum: 519nm
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.