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Rabbit
Anti-CFLIP/AF488
Cat. Number:
bs-8855R-AF488
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists. [provided by RefSeq, Feb 2011]
Also known as:
c FLIP;
c FLIPL;
c FLIPR;
c FLIPS;
c-FLIP;
c-FLIPL;
c-FLIPR;
c-FLIPS;
CASH;
CASP8 and FADD like apoptosis regulator;
CASP8 and FADD-like apoptosis regulator subunit p12;
CASP8AP1;
Caspase homolog;
Caspase like apoptosis regulatory protein;
Caspase related inducer of apoptosis;
Caspase-eight-related protein;
Caspase-like apoptosis regulatory protein;
Casper;
Cellular FLICE-like inhibitory protein;
CFLA;
Cflar;
CFLAR_HUMAN;
CLARP;
FADD like anti apoptotic molecule;
FADD-like antiapoptotic molecule 1;
FLAME;
FLAME-1;
FLAME1;
FLIP;
I FLICE;
I-FLICE;
Inhibitor of FLICE;
MACH-related inducer of toxicity;
MRIT;
OTTHUMP00000163715;
OTTHUMP00000206475;
OTTHUMP00000206476;
OTTHUMP00000206478;
OTTHUMP00000206479;
OTTHUMP00000206480;
OTTHUMP00000206482;
OTTHUMP00000207360;
Usurpin;
Usurpin beta.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with:
(predicted: )
●
Immunogen: KLH conjugated synthetic peptide derived from human CFLIP.
●
Predicted Molecular Weight: 43kDa.
Storage:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Application:
Excitation spectrum: 495nm
Emission spectrum: 519nm
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.