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Rabbit
Anti-INMT/FITC
Cat. Number:
bs-16659R-FITC
Quantity size:
100ul
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Methylation is an important reaction in the metabolism of many drugs, other xenobiotics and endogenous molecules. A methyltransferase is a type of transferase enzyme that transfers a methyl group from a donor to an acceptor. INMT (indolethylamine N-methyltransferase), also known as Temt or aromatic alkylamine N-methyltransferase, is a 264 amino acid protein belonging to the NNMT/PNMT/TEMT family. Localized to the cytoplasm, INMT catalyzes the N-methylation of tryptamine and structurally related compounds. Existing as a monomer, INMT may have a role in the in vivo synthesis of psychoactive compounds or neurotoxins. The gene encoding INMT maps to human chromosome 7p14.3 and mouse chromosome 6 B3.
Also known as:
Amine N methyltransferase;
Amine N-methyltransferase;
Aromatic alkylamine N methyltransferase;
Aromatic alkylamine N-methyltransferase;
Arylamine N methyltransferase;
Arylamine N-methyltransferase;
Indolamine N-methyltransferase;
Indolethylamine N methyltransferase;
Indolethylamine N-methyltransferase;
Inmt;
INMT_HUMAN;
nicotine N methyltransferase;
TEMT;
thioester S methyltransferase like;
Thioether S methyltransferase.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with:
(predicted: )
●
Immunogen: KLH conjugated synthetic peptide derived from human INMT.
●
Predicted Molecular Weight: 29kDa.
Storage:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Application:
Excitation spectrum: 495nm
Emission spectrum: 519nm
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.