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Cat. Number:

bs-16676R-FITC

Quantity size:

100ul

Concentration:

1mg/ml  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

INSM2 is a 566 amino acid nuclear protein. INSM2 is believed to act as a growth or tumor suppressor in certain neurons and in liver cells. INSM2 contains five zinc finger C2H2-type domains which bind nucleic acids. Zinc fingers are composed of 25-30 amino acid residues and have the ability to bind about five nucleotides. C2H2-type zinc fingers have two cysteines on one extremity of the domain, and two histidines on the other extremity. These four cysteines and histidines interact with one zinc atom, resulting in the finger-like conformation of the domain. It is believed that the C2H2-type zinc fingers require the binding of a zinc atom in order for the finger to bind DNA or RNA.

Also known as:

IA 6; IA6; INSM2_HUMAN; Insulinoma associated 2; Insulinoma associated protein 2; mlt1; Zinc finger protein IA 6; Zinc finger protein IA6.

Specificity:

Storage:

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Application:

Excitation spectrum: 495nm
Emission spectrum: 519nm
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.