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Rabbit
Anti-KMT2B/FITC
Cat. Number:
bs-16791R-FITC
Quantity size:
100ul
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known. [provided by RefSeq, Jul 2008]
Also known as:
Histone-lysine N-methyltransferase 2B;
HRX2;
KIAA0304 gene product;
KMT2B;
KMT2B_HUMAN;
Likely ortholog of mouse WW domain binding protein 7;
Lysine N-methyltransferase 2B;
mixed lineage leukemia 4;
Mixed lineage leukemia gene homolog 2 protein;
MLL2;
myeloid lymphoid leukemia 4;
Myeloid lymphoid or mixed lineage leukemia protein 4;
Myeloid/lymphoid or mixed-lineage leukemia protein 4;
Trithorax homolog 2;
trithorax homologue 2;
TRX2;
WBP-7;
WBP7;
WW domain-binding protein 7.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with:
(predicted: )
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Immunogen: KLH conjugated synthetic peptide derived from human KMT2B.
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Predicted Molecular Weight: 293kDa.
Storage:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Application:
Excitation spectrum: 495nm
Emission spectrum: 519nm
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.