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Rabbit
Anti-SPACA3/FITC
Cat. Number:
bs-17615R-FITC
Quantity size:
100ul
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
SPACA3 is a 215 amino acid protein that participates in the fusion and adhesion of sperm and egg plasma membrane during fertilization. Identified as a novel cancer/testis antigen in hematologic malignancies, SPACA3 has the ability to elicit B-cell immune responses in patients with cancer and is considered a potential target for immunotherapy. A member of the glycosyl hydrolase 22 family which is expressed in testis, placenta and epididymis, SPACA3 exists as two alternatively spliced isoforms; SPACA3 isoform 1 is a single-pass type II membrane protein of the sperm acrosome whereas SPACA3 isoform 2 is a secreted protein.
Also known as:
1700025M08Rik;
ALLP17;
Cancer/testis antigen 54;
sperm acrosome associated 3;
CT54;
LYC3;
Lysozyme like sperm specific secretory protein ALLP17;
Lysozyme-like acrosomal sperm-specific secretory protein ALLP-17;
Lysozyme-like protein 3;
LYZL3;
processed form;
SACA3_HUMAN;
SLLP1;
SPACA3;
Sperm acrosome associated 3;
Sperm acrosome membrane-associated protein 3;
Sperm lysozyme-like protein 1;
Sperm protein reactive with antisperm antibodies;
Sperm protein reactive with ASA; 1.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with:
(predicted: )
●
Immunogen: KLH conjugated synthetic peptide derived from human SPACA3.
●
Predicted Molecular Weight: 23kDa.
Storage:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Application:
Excitation spectrum: 495nm
Emission spectrum: 519nm
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.