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Rabbit
Anti-ZFP161/AF555
Cat. Number:
bs-18527R-AF555
Quantity size:
100ul
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
ZFP161 is a 449 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to distinct regions within the nucleus, ZFP161 functions both as a transcriptional repressor of Thymidine Kinase (TK) and c-Myc promoters and as a transcriptional activator of the dopamine transporter (DAT) promoter. ZFP161 contains one BTB (POZ) domain and five C2H2-type zinc fingers which direct its specific localization and nucleic acid binding, respectively. Defects in the gene encoding ZFP161 may be associated with holoprosencephaly type 4 (HPE4), a structural anomaly of the brain characterized by a flattened nasal tip with no visible septum, hypotelorism, lack of nasal bridge, ptosis of the left upper eyelid and, in some cases, infant death.
Also known as:
HZF5;
MGC126126;
ZBTB14;
ZF161_HUMAN;
ZF5;
Zfp 161;
Zfp-161;
Zfp-5;
Zfp161;
Zinc finger and BTB domain containing protein 14;
Zinc finger and BTB domain-containing protein 14;
Zinc finger protein 161 homolog (mouse);
Zinc finger protein 161 homolog;
Zinc finger protein 478;
Zinc finger protein 5;
Zinc finger protein 5 homolog;
Zinc finger protein homologous to Zfp161 in mouse;
ZNF478.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with:
(predicted: )
●
Immunogen: KLH conjugated synthetic peptide derived from human ZFP161.
●
Predicted Molecular Weight: 51kDa.
Storage:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Application:
Excitation spectrum: 556nm
Emission spectrum: 572nm
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.