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Rabbit
Anti-MCF2L2/APC
Cat. Number:
bs-18723R-APC
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
MCF2L2 is a 1,114 amino acid protein that contains one spectrin repeat, one PH domain, one DH domain and one CRAL-TRIO domain. Expressed at high levels in brain and also present in testis and pancreas, MCF2L2 is thought to function as a GEF, catalyzing the activation of target GTPases. Variations in the gene encoding MCF2L2 may be associated with an increased susceptibility to type 2 diabetes. Multiple isoforms of MCF2L2 exist due to alternative splicing events.
Also known as:
ARHGEF22;
Dbs related Rho family guanine nucleotide exchange factor;
Dbs-related Rho family guanine nucleotide exchange factor;
DKFZp686K0690;
DRG;
FLJ42509;
KIAA0861;
MCF.2 cell line derived transforming sequence like 2;
MCF2 transforming sequence like protein 2;
MCF2-transforming sequence-like protein 2;
MCF2L2;
MF2L2_HUMAN;
Probable guanine nucleotide exchange factor MCF2L2;
Rho family guanine nucleotide exchange factor.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with:
(predicted: )
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Immunogen: KLH conjugated synthetic peptide derived from human MCF2L2.
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Predicted Molecular Weight: 127kDa.
Storage:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Application:
Excitation spectrum: 650nm
Emission spectrum: 660nm
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.