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Cat. Number:

bs-19298R-FITC

Quantity size:

100ul

Concentration:

1mg/ml  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

HSCARG is a 299 amino acid redox sensor protein that belongs to the NmrA-type oxidoreductase family. Localizing primarily to the cytoplasm and perinuclear region, HSCARG localization to the nucleus may occur with increased intracellular nitric oxide and reduced NADPH/NADP+ ratios. Existing as a homodimer, HSCARG interacts with ASS1, inhibiting ASS1 activity in the presence of low NADPH/NADP+ ratios. HSCARG gets induced by nitric oxide, cGMP and proinflammatory cytokines. The gene encoding HSCARG maps to human chromosome 16p13.3 and mouse chromosome 16 A1. Overexpression of the gene encoding HSCARG results in increased cell viability.

Also known as:

FLJ25918; HSCARG; NmrA like family domain containing 1; NmrA like family domain containing protein 1; NmrA-like family domain-containing protein 1; NMRAL1; NMRL1_HUMAN; SDR48A1.

Specificity:

Storage:

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Application:

Excitation spectrum: 495nm
Emission spectrum: 519nm
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.