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Rabbit
Anti-Site 2 protease/Gold
Cat. Number:
bs-19356R-Gold
Quantity size:
100ul
10nm
Concentration:
0.4mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome); IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.[provided by RefSeq, Aug 2009]
Also known as:
BRESEK;
Endopeptidase S2P;
IFAP;
KFSDX;
MBTP2_HUMAN;
MBTPS2;
Membrane bound transcription factor site 2 protease;
membrane-bound transcription factor peptidase, site 2;
membrane-bound transcription factor protease, site 2;
Membrane-bound transcription factor site-2 protease;
S2P;
S2P endopeptidase;
Site 2 protease;
SREBPs intramembrane protease;
Sterol regulatory element-binding proteins intramembrane protease.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with:
(predicted: )
●
Immunogen: KLH conjugated synthetic peptide derived from human Site 2 protease.
●
Predicted Molecular Weight: 57kDa.
Storage:
0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
Application:
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.