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Rabbit
Anti-phospho-Parkin (Ser65)/Gold
Cat. Number:
bs-19882R-Gold
Quantity size:
100ul
35nm
Concentration:
0.4mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. [provided by RefSeq, Jul 2008]
Also known as:
Parkin (phospho S65); p-Parkin (phospho S65);
AR JP;
E3 ubiquitin ligase;
E3 ubiquitin protein ligase parkin;
E3 ubiquitin-protein ligase parkin;
FRA6E;
LPRS 2;
LPRS2;
PARK 2;
PARK2;
Parkin 2;
Parkinson disease (autosomal recessive juvenile) 2;
Parkinson disease (autosomal recessive, juvenile) 2, parkin;
Parkinson disease protein 2;
Parkinson juvenile disease protein 2;
Parkinson protein 2 E3 ubiquitin protein ligase;
Parkinson protein 2, E3 ubiquitin protein ligase (parkin);
PDJ;
PRKN 2;
PRKN;
PRKN2;
PRKN2_HUMAN;
Ubiquitin E3 ligase PRKN.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with:
(predicted: )
●
Immunogen: KLH conjugated synthesised phosphopeptide derived from human Parkin around the phosphorylation site of Ser65..
●
Predicted Molecular Weight: 52kDa.
Storage:
0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
Application:
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.