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Rabbit
Anti-phospho-Src (Ser75)/PE-Cy7
Cat. Number:
bs-19893R-PE-Cy7
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Also known as:
Src (phospho S75); Src (phospho Ser75); p-Src (phospho S75); ASV;
Avian sarcoma virus;
c SRC;
CDNA FLJ14219 fis clone NT2RP3003800 highly similar to Rattus norvegicus tyrosine protein kinase pp60 c src mRNA;
cSrc;
EC 2.7.10.2;
Neuronal CSRC tyrosine specific protein kinase;
Neuronal SRC;
Oncogene SRC;
OTTHUMP00000174476;
OTTHUMP00000174477;
p60 Src;
p60-Src;
p60Src;
pp60c src;
pp60c-src;
pp60csrc;
Proto oncogene tyrosine protein kinase Src;
Proto-oncogene c-Src;
Proto-oncogene tyrosine-protein kinase Src;
Protooncogene SRC;
Protooncogene SRC Rous sarcoma;
Src;
SRC Oncogene;
SRC proto oncogene non receptor tyrosine kinase;
SRC_HUMAN;
SRC1;
Tyrosine kinase pp60c src;
Tyrosine protein kinase SRC 1;
Tyrosine protein kinase SRC1;
v src avian sarcoma (Schmidt Ruppin A2) viral oncogene homolog;
V src sarcoma (Schmidt Ruppin A 2) viral oncogene homolog (avian);
v src sarcoma (Schmidt Ruppin A 2) viral oncogene homolog avian.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with:
(predicted: )
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Immunogen: KLH conjugated synthesised phosphopeptide derived from human Src around the phosphorylation site of Ser75.
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Predicted Molecular Weight: 61kDa.
Storage:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Application:
Excitation spectrum: 488nm,561nm,743nm
Emission spectrum: 785nm
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.