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Rabbit
Anti-POU2F3/PE-Cy5
Cat. Number:
bs-21046R-PE-Cy5
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
This gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type-specific differentiation pathways. The encoded protein is primarily expressed in the epidermis, and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
Also known as:
class 2;
Epoc 1;
Epoc1;
HGNC19864;
Oct 11;
Oct-11;
OCT11;
Octamer binding transcription factor 11;
Octamer-binding protein 11;
Octamer-binding transcription factor 11;
OTF-11;
PLA 1;
PLA1;
PLA1 protein;
PO2F3_HUMAN;
POU class 2 homeobox 3;
POU domain;
POU domain transcription factor OCT11a;
POU domain, class 2, transcription factor 3;
POU transcription factor;
POU2F3;
Skn 1a;
transcription factor 3;
Transcription factor PLA-1;
Transcription factor Skn-1;
Transcription factor Skn1.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with:
(predicted: )
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Immunogen: KLH conjugated synthetic peptide derived from human POU2F3.
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Predicted Molecular Weight: 47kDa.
Storage:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Application:
Excitation spectrum: 488nm,561nm,649nm
Emission spectrum: 667nm
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.