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Rabbit
Anti-PKLR/Gold
Cat. Number:
bs-12694R-Gold
Quantity size:
100ul
10nm
Concentration:
0.4mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Also known as:
EC 2.7.1.40;
KPYR_HUMAN;
L-PK;
Pk-1;
PK1;
PKL;
Pklg;
Pklr;
PKR;
PKRL;
Pyruvate kinase 1;
Pyruvate kinase isozymes R/L;
Pyruvate kinase liver and blood cell;
Pyruvate kinase liver and RBC;
Pyruvate kinase liver and red blood cell;
Pyruvate kinase liver type;
Pyruvate kinase type L;
Pyruvate kinase, red cell type;
R type/L type pyruvate kinase;
R-PK;
R-type/L-type pyruvate kinase;
Red cell/liver pyruvate kinase;
RPK.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with:
(predicted: )
●
Immunogen: KLH conjugated synthetic peptide derived from human PKLR.
●
Predicted Molecular Weight: 62kDa.
Storage:
0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
Application:
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.