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Rabbit
Anti-Syntaxin 1A + Syntaxin 1B/FITC
Cat. Number:
bs-20574R-FITC
Quantity size:
100ul
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Syntaxins are potentially involved in the docking of synaptic vesicles at presynaptic active zones and may play a key role in neurotransmitter exocytosis. Three isoforms are produced by alternative splicing. Isoform 1 is expressed in embryonic spinal chord and ganglia and in adult cerebellum and cerebral cortex. Isoform 2 is expressed in heart, liver, fat, skeletal muscle, kidney and brain. Syntaxin 1A interacts with VAPA and SYBU and is a member of the SNARE core complex containing SNAP25 and VAMP2. In addition, it is found in complexes with SNAP25, SNAP23 and VAMP8. Haploinsufficiency of STX1A may result in particular cardiovascular and musculo-skeletal abnormalities observed in Williams-Beuren syndrome, a rare developmental disorder.
Also known as:
HPC 1;
Neuron specific antigen HPC 1;
Neuron specific antigen HPC1;
Neuron-specific antigen HPC-1;
OTTHUMP00000174615;
OTTHUMP00000174616;
OTTHUMP00000174617;
OTTHUMP00000174618;
P35 1;
P35-1;
STX 1;
STX 1A;
STX1;
STX1A;
STX1A_HUMAN;
SYN1A;
Syntaxin 1A (brain);
Syntaxin 1A;
Syntaxin 1A brain;
Syntaxin-1A;
STX1B_HUMAN; Syntaxin 1B; Syntaxin-1B1; Syntaxin-1B2; Syntaxin 1B1; Syntaxin 1B2; STX1B; STX1B1; STX1B2.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with:
(predicted: )
●
Immunogen: KLH conjugated synthetic peptide derived from human Syntaxin 1A + Syntaxin 1B.
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Predicted Molecular Weight: 33kDa.
Storage:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Application:
Excitation spectrum: 495nm
Emission spectrum: 519nm
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.