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Rabbit
Anti-HIF-1 Alpha/FITC
Cat. Number:
bs-20399R-FITC
Quantity size:
100ul
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator(ARNT). This gene encodes the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. Two alternative transcripts encoding different isoforms have been identified.
Also known as:
ARNT interacting protein;
ARNT-interacting protein;
Basic helix loop helix PAS protein MOP1;
Basic-helix-loop-helix-PAS protein MOP1;
bHLHe78;
Class E basic helix-loop-helix protein 78;
HIF 1A;
HIF 1alpha;
HIF-1-alpha;
HIF1 A;
HIF1 Alpha;
HIF1;
HIF1-alpha;
HIF1A;
HIF1A_HUMAN;
Hypoxia inducible factor 1 alpha;
Hypoxia inducible factor 1 alpha isoform I.3;
Hypoxia inducible factor 1 alpha subunit;
Hypoxia inducible factor 1 alpha subunit basic helix loop helix transcription factor;
Hypoxia inducible factor 1, alpha subunit (basic helix loop helix transcription factor);
Hypoxia inducible factor1alpha;
Hypoxia-inducible factor 1-alpha;
Hypoxia-inducible factor-1a;
Member of PAS protein 1;
Member of PAS superfamily 1;
Member of the PAS Superfamily 1;
MOP 1;
MOP1;
PAS domain-containing protein 8;
PASD 8;
PASD8.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with:
(predicted: )
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Immunogen: KLH conjugated synthetic peptide derived from human HIF-1 Alpha.
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Predicted Molecular Weight: 92kDa.
Storage:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Application:
Excitation spectrum: 495nm
Emission spectrum: 519nm
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.