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Mouse
Anti-Alpha-actinin-1/Biotin
Cat. Number:
bsm-33272M-Bio
Quantity size:
100ul
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Also known as:
ACTN 1;
ACTN1_HUMAN;
Alpha Actinin 1;
Alpha actinin cytoskeletal isoform;
Alpha-actinin cytoskeletal isoform;
Alpha-actinin-1;
FLJ40884;
FLJ54432;
Actinin Alpha 1;
F-Actin Cross-Linking Protein;
Non-Muscle Alpha-Actinin-1;
Actinin, Alpha 1;
Actinin 1 Smooth Muscle;
BDPLT15;
Specificity:
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Mouse Monoclonal(Clone number:6A10) IgG, affinity purified by Protein G.
●
Reacts with:
(predicted: )
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Immunogen: Recombinant human Alpha-actinin-1 protein.
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Predicted Molecular Weight: 103kDa.
Storage:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Application:
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.