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Recombinant human Vcam1 protein, C-His
Catalog Number:
bs-10858P
General Information
QC Testing
Purity:
>95% as determined by SDS-PAGE
Concentration:
>0.5 mg/ml
Usage Guide
Storage:
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
Background:
VCAM1 is important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with the integrins alpha4 beta1 (beta 1 integrin VLA4) and alpha4 beta7 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. VCAM1 is also expressed by several non endothelial cell types including some macrophages, follicular dendritic cells and bone marrow, stromal cells.
Figures
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.