www.bioss.com.cn
400-901-9800
sales@bioss.com.cn
techsupport@bioss.com.cn
400-901-9800
sales@bioss.com.cn
techsupport@bioss.com.cn
Rabbit
Anti-ERK2/PE-Cy5.5
Cat. Number:
bsm-52068R-PE-Cy5.5
Quantity size:
100ul
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jan 2014]
Also known as:
Mitogen-Activated Protein Kinase 1;
Extracellular Signal-Regulated Kinase 2;
Mitogen-Activated Protein Kinase 2;
MAP Kinase Isoform P42;
MAP Kinase 1;
MAP Kinase 2;
EC 2.7.11.24;
P42-MAPK;
MAPK 2;
PRKM1;
PRKM2;
ERK-2;
ERK2;
ERT1;
Protein Tyrosine Kinase ERK2;
EC 2.7.11;
P42MAPK;
P41mapk;
MAPK 1;
MAPK2;
P38;
P40;
ERK;
P41;
MK01_HUMAN;
Specificity:
●
Rabbit Monoclonal(Clone number:3G1) IgG, affinity purified by Protein A.
●
Reacts with:
(predicted: )
●
Immunogen: KLH conjugated synthetic peptide derived from human ERK2.
●
Predicted Molecular Weight: 42kDa.
Storage:
Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.05M PB, pH 7.5. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Application:
Excitation spectrum: 496,564nm,675nm
Emission spectrum: 578nm,695nm
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.