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Catalog Number:

bs-41232P

Species:

Human

Host:

E.coli

AA Seq:

1-105/105

Predicted MW:

55

Detected MW:

60 kDa

Tags:

His & MBP

Activity:

Not tested

Endotoxin:

Not analyzed

Purity:

>95% as determined by SDS-PAGE

Purification:

AC

Concentration:

＞0.5 mg/ml

Storage:

Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.

Background:

Cytochrome C is an electron transporting protein that resides within the intermembrane space of the mitochondria, where it plays a critical role in the process of oxidative phosphorylation and production of cellular ATP. An increasing amount of interest has been directed toward the role which cytocrome C has been demonstrated to play in apoptotic processes. Following exposure to apoptotic stimuli, cytochrome C is rapidly released from the mitochondria into the cytosol, an event which may be required for the completion of apoptosis in some systems. Cytosolic cytochrome C functions in the activation of caspase 3, an ICE family molecule that is a key effector of apoptosis.