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Catalog Number:

bs-46110P-Biotin

Species:

Human

Host:

HEK293 cell

AA Seq:

1-740/805

Predicted MW:

86.28

Detected MW:

100-110 kDa

Tags:

C-His

Activity:

Not tested

Endotoxin:

Not analyzed

Purity:

>90% as determined by SDS-PAGE

Purification:

AC

Concentration:

＞0.5 mg/ml

Storage:

Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.

Background:

The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. [provided by RefSeq, Jul 2008].