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Rabbit
Anti-Laminin 5/Gold
Cat. Number:
bs-6713R-Gold
Quantity size:
100ul
10nm
Concentration:
0.4mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
Laminin-5 is thought to be involved in (1) cell adhesion via integrin alpha-3/beta-1 in focal adhesion and integrin alpha-6/beta-4 in hemidesmosomes, (2) signal transduction via tyrosine phosphorylation of pp125-FAK and p80, (3) differentiation of keratinocytes.
Tissue specificity;
Skin; respiratory, urinary, and digestive epithelia and in other specialized tissues with prominent secretory or protective functions. Epithelial basement membrane, and epithelial cell tongue that migrates into a wound bed. A differential and focal expression of the subunit alpha-3 is observed in the CNS.
Also known as:
E170;
Epiligrin 170 kDa subunit;
Epiligrin subunit alpha;
Kalinin subunit alpha;
LAMA3;
LAMA3A;
Laminin 5 alpha3;
Laminin A3;
laminin alpha 3;
laminin alpha3;
Laminin subunit alpha-3;
Laminin-5 subunit alpha;
Laminin-6 subunit alpha;
Laminin-7 subunit alpha;
laminin5 alpha 3;
Laminin5 alpha3;
LAMNA;
LOCS;
Nicein subunit alpha
LAMA3_HUMAN.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with:
(predicted: )
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Immunogen: KLH conjugated synthetic peptide derived from human Laminin 5.
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Predicted Molecular Weight: 367kDa.
Storage:
0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
Application:
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.