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CLDN1 Antibody Blocking Peptide
Catalog Number:
bs-1428P
General Information
Species:
mouse
QC Testing
Activity:
Not tested
Purification:
1
Usage Guide
Storage:
Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background:
bs-1428P is one synthetic peptide derived from mouse Claudin 1.
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. [provided by RefSeq].
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. [provided by RefSeq].
Figures
VALIDATION IMAGES
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.