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Rabbit
Anti-BMPR2/AF555
Cat. Number:
bs-4237R-AF555
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP-7, BMP-2 and, less efficiently, BMP-4. Binding is weak but enhanced by the presence of type I receptors for BMPs.
Also known as:
BMP type II receptor;
BMP type-2 receptor;
BMPR 2;
BMPR 3;
BMPR II;
BMPR-2;
BMPR-II;
Bmpr2;
BMPR2_HUMAN;
BMPR3;
BMPRII;
BMR 2;
BMR2;
Bone morphogenetic protein receptor type 2;
Bone morphogenetic protein receptor type II;
Bone morphogenetic protein receptor type-2;
Bone morphogenic protein receptor type II serine threonine kinase;
BRK 3;
BRK3;
PPH 1;
PPH1;
Serine threonine kinase type II activin receptor like kinase;
T ALK;
TALK;
Type II activin receptor like kinase.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with:
(predicted: )
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Immunogen: KLH conjugated synthetic peptide derived from human BMPR2.
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Predicted Molecular Weight: 112kDa.
Storage:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Application:
Excitation spectrum: 556nm
Emission spectrum: 572nm
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.