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COMP Antibody Blocking Peptide
Catalog Number:
bs-3679P
General Information
Species:
human
QC Testing
Activity:
Not tested
Purification:
HPLC
Usage Guide
Storage:
Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background:
COMP is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF like and calcium binding (thrombospondin like) domains. Oligomerization results from formation of a five stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).
Figures
VALIDATION IMAGES
 
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.