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Catalog Number:

bs-0738P

Species:

human

Activity:

Not tested

Purification:

HPLC

Storage:

Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.

Background:

Livin is a novel member of the IAP protein family and contains a single baculoviral IAP repeat (BIR) domain and a RING finger domain and has two isoforms termed Livin alpha and Livin beta. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. The two isoforms of Livin appear to have different functions and tissue distributions.