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Catalog Number:

bs-0026P

Species:

mouse

Activity:

Not tested

Purification:

1

Storage:

Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.

Background:

Osteopontin is the principal phosphorylated glycoprotein of bone and is expressed in a limited number of other tissues including dentine. Osteopontin is produced by osteoblasts under stimulation by calcitriol and binds tightly to hydroxyapatite. It is also involved in the anchoring of osteoclasts to the mineral of bone matrix via the vitronectin receptor, which has specificity for osteopontin. Osteopontin is overexpressed in a variety of cancers, including lung, breast, colorectal, stomach, ovarian, melanoma and mesothelioma.