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Rabbit
Anti-KSR1/Gold
Cat. Number:
bs-3549R-Gold
Quantity size:
100ul
15nm
Concentration:
0.4mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
KSR1 is a molecular scaffold and positive regulator of the Raf/MEK/ERK phosphorylation cascade. It was initially considered to be a protein kinase acting in the Ras pathway. KSR1 is required for maximal ERK activation induced by growth factors and by some cytotoxic agents. In resting cells, phosphorylated KSR1 is cytoplasmic and in stimulated cells, dephosphorylated KSR1 is membrane associated.
Also known as:
BKSR 1;
BKSR1;
dKsr;
EK 31;
EK31;
hb;
Kinase suppressor of Ras 1;
Kinase suppressor of ras;
KSR 1;
KSR;
KSR1;
KSR1_HUMAN;
Positive Ras signaling mediator family member (86.4 kD);
Positive Ras signaling mediator family member;
RSU 2;
RSU2;
SR 31;
SR31;
Suppressor of activated let 60 Ras SUR3;
Suppressor of Ras1 31
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with:
(predicted: )
●
Immunogen: KLH conjugated synthetic peptide derived from human KSR1 (584-638)aa.
●
Predicted Molecular Weight: 101kDa.
Storage:
0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
Application:
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.