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Rabbit
Anti-RET/AP
Cat. Number:
bs-2793R-AP
Quantity size:
100ul
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed. [provided by RefSeq, Jul 2008]
Also known as:
Ret Proto-Oncogene;
Cadherin-Related Family Member 16;
Rearranged During Transfection;
RET Receptor Tyrosine Kinase;
Cadherin Family Member 12;
Proto-Oncogene C-Ret;
EC 2.7.10.1;
CDHF12;
CDHR16;
RET51;
PTC;
Ret Proto-Oncogene (Multiple Endocrine Neoplasia And Medullary Thyroid Carcinoma 1, Hirschsprung Disease) ;
Multiple Endocrine Neoplasia And Medullary Thyroid Carcinoma 1;
Proto-Oncogene Tyrosine-Protein Kinase Receptor Ret;
Hydroxyaryl-Protein Kinase;
RET Transforming Sequence;
Receptor Tyrosine Kinase;
Hirschsprung Disease 1;
Oncogene RET;
EC 2.7.10;
RET-ELE1;
MEN2B;
HSCR1;
MEN2A;
MTC1; RET_HUMAN.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with:
(predicted: )
●
Immunogen: KLH conjugated synthetic peptide derived from human RET.
●
Predicted Molecular Weight: 122kDa.
Storage:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Application:
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.