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Rabbit
Anti-Peroxiredoxin 3/Gold
Cat. Number:
bs-1874R-Gold
Quantity size:
100ul
35nm
Concentration:
0.4mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The Peroxiredoxin (Prdx, Prx, or Trx-Px) family of enzymes is a recently identified family of peroxidases found in free-living organisms. The six known isoforms (Prx1-6) play an important role in protecting lipids, enzymes and DNA against peroxides, such as hydrogen peroxide. The ubiquitously expressed peroxiredoxins have also been shown to play a role in apoptosis and cell differentiation. This is acomplished by the active cysteine of Prx reducing peroxides, which is then converted into a transient cysteine sulfenic acid or cysteine sulfinic acid. If Prx protection is inadequate against peroxidases, the resulting protein and DNA damage may result in neurological disease such as Alzheimer's or DNA damage leading to cancer.
Also known as:
Antioxidant protein 1;
AOP 1;
AOP-1;
AOP1;
HBC189;
MER5;
MGC104387;
MGC24293;
mitochondrial;
Peroxiredoxin III;
Peroxiredoxin-3;
PRDX3;
PRDX3_HUMAN;
PRO1748;
Protein MER5 homolog;
PRX III;
Prx-III;
PRX3;
SP 22;
SP-22;
SP22;
Thioredoxin dependent peroxide reductase mitochondrial;
Thioredoxin-dependent peroxide reductase.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with:
(predicted: )
●
Immunogen: KLH conjugated synthetic peptide derived from human PRDX3.
●
Predicted Molecular Weight: 21kDa.
Storage:
0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
Application:
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.