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Rabbit
Anti-ERK1/FITC
Cat. Number:
bs-1020R-FITC
Quantity size:
100ul
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq, Jul 2008]
Also known as:
ERK;
ERK-1;
ERT 2;
ERT2;
Extracellular Signal Regulated Kinase 1;
Extracellular signal related kinase 1;
Extracellular signal-regulated kinase 1;
HGNC6877;
HS44KDAP;
HUMKER1A;
Insulin Stimulated MAP2 Kinase;
Insulin-stimulated MAP2 kinase;
MAP kinase 1;
MAP kinase 3;
MAP Kinase;
MAP kinase isoform p44;
MAPK 1;
MAPK 3;
MAPK;
MAPK1;
Mapk3;
MGC20180;
Microtubule Associated Protein 2 Kinase;
Microtubule-associated protein 2 kinase;
Mitogen Activated Protein Kinase 3;
Mitogen-activated protein kinase 1;
Mitogen-activated protein kinase 3;
MK03_HUMAN;
OTTHUMP00000174538;
OTTHUMP00000174541;
p44 ERK1;
p44 MAPK;
p44-ERK1;
p44-MAPK;
P44ERK1;
P44MAPK;
PRKM 3;
PRKM3;
Protein Kinase Mitogen Activated 3.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with:
(predicted: )
●
Immunogen: KLH conjugated synthetic peptide derived from human MAPK1.
●
Predicted Molecular Weight: 43kDa.
Storage:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Application:
Excitation spectrum: 495nm
Emission spectrum: 519nm
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.