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Cat. Number:

bs-12100R-FITC

Quantity size:

100ul

Concentration:

1mg/ml  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

NR3A is a subunit of the N-methyl-D-aspartate (NMDA) receptors, which belong to the superfamily of glutamate-regulated ion channels and function in pathological and physiological processes in the central nervous system. NR3A is a multi-pass membrane protein that is expressed in fetal brain and is mediated by glycine. It may be involved in the development of dendritic spines and in the PPP2CB-NMDAR mediated signaling mechanism. NR3A forms a heteromeric channel composed of a Ω subunit (GRIN1), an e subunit (GRIN2A, GRIN2B, GRIN2C or GRIN2D) and a third subunit (GRIN3A or GRIN3B). The NR3A protein is enriched in post-synaptic plasma membrane and post-synaptic densities and requires the presence of GRIN1 to be targeted at the plasma membrane. The NR3A subunit displays greater than 90% sequence homology to the corresponding subunit in rat.

Also known as:

Chi-1; Glutamate [NMDA] receptor subunit 3A; GRIN3A; N-methyl-D-aspartate receptor; N-methyl-D-aspartate receptor subtype 3A; NMD3A_HUMAN; NMDAR-L; NMDAR-L1; NMDAR3A; NR3A.

Specificity:

Storage:

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Application:

Excitation spectrum: 495nm
Emission spectrum: 519nm
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.