JUNB Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF,ICC/IF | Bioss

bsm-60454R

重组兔单抗

JUNB Recombinant Rabbit mAb

活化蛋白激酶B重组兔单抗

AP-1; JUNB_HUMAN; JUNB; Transcription factor AP-1 subunit JunB; JUNB_MOUSE; MyD21; Jun-b; JUNB_RAT; JunB proto-oncogene, AP-1 transcription factor subunit

Rabbit

IgG

Liquid

affinity purified by Protein A

Recombinant

C5F3

42-44 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Jun-B属于转录因子AP-1家族(Jun蛋白家族包括c-Jun、JunB和JunD）

The cJun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus vjun oncogene. JunB and JunD have been shown to be almost identical to cJun in their C terminal regions, which are involved in dimerization and DNA binding, whereas their N terminal domains, which are involved in transcriptional activation, diverge. JunB is a transcription factor involved in regulating gene activity following the primary growth factor response. It binds to the DNA sequence 5'-TGA[CG]TCA-3'.

JUNB

Transcription factor jun-B

Binds DNA as a homodimer or as a heterodimer with another member of the Jun/Fos family. Interacts with ITCH (via its WW domains).

Nucleus.

Ubiquitinated by ITCH, leading to its degradation.

Belongs to the bZIP family. Jun subfamily.
Contains 1 bZIP (basic-leucine zipper) domain.

Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[CG]TCA-3'.